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Brand Names:
Sirdalud Retard, Zanaflex
What is Tizanidine?
Tizanidine is a centrally acting alpha2-adrenergic agonist. It is a skeletal muscle relaxant used for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.
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429 patients in the community are taking or have taken Tizanidine.
| Reason | # Patients | Percentage of patients |
|---|---|---|
| Stiffness/spasticity | 291 | 67% |
| Other | 45 | 10% |
| Pain | 18 | 4% |
| disease-related symptoms | 14 | 3% |
| Muscle Spasms, feet and toes | 5 | 1% |
| Spasms | 4 | <1% |
| Muscle spasms, neck and shoulders | 4 | <1% |
| General health | 3 | <1% |
| Slow my MS progress | 3 | <1% |
| Fasciculations | 3 | <1% |
| Insomnia | 2 | <1% |
| Depression | 2 | <1% |
| MS Hug, or girdle-band sensation, stomach/chest/thighs | 1 | <1% |
| Pain, leg | 1 | <1% |
| Burning sensation, soles of feet | 1 | <1% |
| Headaches/ Migraines | 1 | <1% |
| Muscle twitching (fasciculations) | 1 | <1% |
| Spasms, calves | 1 | <1% |
| Night-time leg spasms | 1 | <1% |
| Fatigue | 1 | <1% |
| Muscle cramping, spasms | 1 | <1% |
| twitches and jerks | 1 | <1% |
| Sexual dysfunction | 1 | <1% |
| Calf, feet cramps and muscle spasms | 1 | <1% |
| Cramps, calf muscles | 1 | <1% |
| tonic spasm | 1 | <1% |
| Muscle tension | 1 | <1% |
| Don't know | 1 | <1% |
| Mobility | 1 | <1% |
| Treat Parkinson's | 1 | <1% |
| Support another treatment | 1 | <1% |
| 0 mg day | 0 mg none | 1 mg day | 0 mg none | 2 mg day | 3 mg day | 3 day | 0 mg none | 4 mg day | 5 mg day | 6 mg day | 8 mg day | 10 mg day | 12 mg day | 14 mg day | 16 mg day | 18 mg day | 20 mg day | 24 mg day | 28 mg day | 30 mg day | 32 mg day | 40 mg day | 50 mg day | 100 mg day | 300 mg day | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
41
|
13
|
1
|
1
|
27
|
3
|
1
|
4
|
100
|
6
|
20
|
48
|
8
|
25
|
2
|
25
|
6
|
10
|
15
|
2
|
4
|
5
|
1
|
1
|
2
|
2
|
||
How long current patients have been taking Tizanidine or how long patients were taking Tizanidine before stopping.
Results from 32 patient evaluations. See the overall results and all individual evaluations.
| Major | 46% | 11 |
|---|---|---|
| Moderate | 33% | 8 |
| Slight | 13% | 3 |
| None | 8% | 2 |
Insomnia
| Severe | 9% | 3 |
|---|---|---|
| Moderate | 34% | 11 |
| Mild | 25% | 8 |
| None | 31% | 10 |
Top reported side-effects include: sleepy, Fatigue, makes me very sleepy
Summary results are based on 32 individual responses. For more information, see overall results for Adherence, Burden and Cost.